Vogelarena

Log In
 


Gebruikersnaam

Paswoord

Onthouden

Paswoord vergeten

Schrijf mij in!

 

 

 

 

 

 

 

   
Inhoud
   

   
Zoeken
 
   
 
   
VogelArena.com
 

E-mail


   
Reclame
 





   




Forums Home > Kweek en verzorging. > veroorzaker van maag dilletatiesyndroom gevonden Moderators
agabird


Om een bericht te kunnen posten moet u ingeschreven zijn schrijf in.
Als U al lid bent log hier in.

Pagina : 1


Auteur Onderwerp : veroorzaker van maag dilletatiesyndroom gevonden
rajar
Website Member
Posts :709

Website Member
2008-08-13 - 18:53:10 send message to rajar



Researchers at the University of California, San Francisco, have identified a virus behind the mysterious infectious disease that has been killing parrots and exotic birds for more than 30 years.

The team, led by UCSF professors Joseph DeRisi, PhD, and Don Ganem, MD, also has developed a diagnostic test for the virus linked to Proventricular Dilation Disease, or PDD, which will enable veterinarians worldwide to control the spread of the virus.

Results of the study will be published in Virology Journal and will appear online in August. The findings also will be presented in full at the Aug. 11 annual meeting of the Association of Avian Veterinarians, in Savannah, Ga.

The new virus, which the team named Avian Bornavirus (ABV), is a member of the bornavirus family, whose other members cause encephalitis in horses and livestock. Working with veterinarians on two continents, the group isolated this virus in 71 percent of the samples from infected birds, but none of the healthy individuals.

"This discovery has potentially solved a mystery that has been plaguing the avian veterinary community since the 1970s," said DeRisi, a molecular biologist whose laboratory aided in the 2003 discovery of the virus causing Severe Acute Respiratory Syndrome, or SARS, in humans. "These results clearly reveal the existence of an avian reservoir of remarkably diverse bornaviruses that are dramatically different from anything seen in other animals."

The discovery could have profound consequences on both domesticated parrots and in the conservation of endangered species, according to DeRisi and Ganem, both Howard Hughes Medical Institute investigators at UCSF. Those species include the Spix's Macaw, currently one of the most endangered birds in the world, whose number has dwindled to roughly 100 worldwide and whose continued existence is threatened by PDD.

The research was spearheaded by Amy Kistler, a postdoctoral fellow in the DeRisi and Ganem labs. Together with veterinarians Susan Clubb, in the United States, and Ady Gancz in Israel, Kistler analyzed affected birds using UCSF's patented ViroChip technology.

The ViroChip, which DeRisi and Ganem developed, is a high-throughput screening technology that uses a DNA microarray to test viral samples. The team was able to recover virus sequence from a total of 16 diseased birds from two different continents. The complete genome sequence of one isolate was captured using ultra deep sequencing.

The virus they identified is highly divergent from all previously identified members of the "Bornaviridae" family and represents the first full-length bornavirus genome ever cloned directly from avian tissue. Analysis of the Avian Bornavirus genome revealed at least five distinct varieties.

PDD is a fatal disease that causes nervous system disorders in both domesticated and wild birds in the psittacine, or parrot, family worldwide. The disease has been found in 50 different species of parrots, as well as five other orders of birds, and is widely considered to be the greatest threat to captive breeding of birds in this family, the researchers said.

The disorder often leads to the birds' inability to swallow and digest food, with resulting wasting; many birds also suffer from neurologic symptoms such as imbalance and lack of coordination. Regardless of the clinical course the disease takes, it is often fatal.

Scientists have theorized for decades that a viral pathogen was the source of the disease, but until now, no one had been able to identify the likely culprit.

"This provides a very compelling lead in the long-standing search for a viral cause of PDD," Ganem said. "With the development of molecular clones and diagnostic tests for ABV, we can now begin to explore both the epidemiology of the virus and how it is linked to the disease state."

Co-authors on the paper include Amy L. Kistler, Peter Skewes-Cox, Kael Fisher, Katherine Sorber, Charles Y. Chiu and Alexander Greninger, from the Howard Hughes Medical Institute and Department of Biochemistry, Microbiology and Medicine at UCSF; Ady Gancz, from The Exotic Clinic, Herzlyia, Israel; Susan Clubb, Rainforest Clinic for Birds and Exotics, Loxahatchee, Fla.; Avishai Lublin, Sara Mechani and Yigal Farnoushi, of the Division of Avian and Fish Diseases, Kimron Veterinary Institute, bet Dagan, Israel; and Scott B. Karlene, of the Lahser Interspecies Research Foundation, Bloomfield Hills, Mich.

The research was supported by funding to DeRisi and Ganem from the Howard Hughes Medical Institute and the Doris Duke Charitable Foundation. Funding for US specimen collection and veterinary care was provided by the Lahser Interspecies Research Foundation

The DeRisi Laboratory is part of the California Institute for Quantitative Biosciences, known as QB3, a cooperative effort among private industry and more than 180 scientists at UCSF, UC Berkeley and UC Santa Cruz. The collaboration harnesses the quantitative sciences to integrate and enhance scientific understanding of biological systems at all levels, enabling scientists to tackle problems that have been previously unapproachable.

UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. For further information, please visit www.ucsf.edu.





medaar
Geroyeerd
Posts :1001

Geroyeerd
2008-08-13 - 20:55:03 send message to medaar

IN HET WESTVLAAMS IS BETER ZE ... Ben nie rap. van tijpen.


P.Rooth
Website Member
Posts :2793

Website Member
2008-08-14 - 20:23:41 send message to P.Rooth

Dat er slechts een enkeling reageert op deze topic vind ik raar en ook weer niet .
Heb je nooit te maken gehad met kliermaagenz.enz.
Behoor je net zoals mij tot de gelukkigen .

ben je een keer getroffen door deze ellendige ziekte in je vogels had je gehoopt dat er eerder de dader van deze ziekte ontdekt was .

Nu de mogelijkheid nog op genezing en dan maar weer hopen dat de geneesmiddelen snel toegelaten worden .

Al met al een heuglijk feit .happy :)happy :)happy :)

Paul


wiechmann
Website Member
Posts :944

Website Member
2008-08-14 - 21:01:13 send message to wiechmann

al zal er om te beginnen maar een test zijn dat zal voor de nieuwe koper al veel elende besparen.

en als er dadelijk een test is ben ik zeer nieuwsgierig hoeveel vogels er dan als nog verkocht gaan worden om er nog geld van te kunnen krijgen zal weer veel elenende geven in vogel land


vogelboet
Website Member
Posts :3

Website Member
2008-08-14 - 21:05:56 send message to vogelboet

hallo best wel intresant maar ik ken geen engels
maar we hebben zo veel geleerde mensen in ons bestand die vertalen het wel even b v d roel vogelboet alkmaar


rajar
Website Member
Posts :709

Website Member
2008-08-14 - 21:21:58 send message to rajar



rajar
Website Member
Posts :709

Website Member
2008-08-14 - 21:29:06 send message to rajar

summiere vertaling met dank aan google

0 op artikel in Virologie
www.eurekalert.org
Researchers at the University of California, San Francisco, have identified a virus behind the mysterious infectious disease that has been killing parrots and exotic birds for more than 30 years. Onderzoekers aan de Universiteit van California, San Francisco, hebben een virus achter de mysterieuze besmettelijke ziekte die is gedood papegaaien en exotische vogels meer dan 30 jaar. The team, led by UCSF professors Joseph DeRisi, PhD, and Don Ganem, MD, also has developed a diagnostic test for the virus linked to Proventricular Dilation Disease, or PDD, which will enable veterinarians worldwide to control the spread of the virus. Het team, geleid door Joseph UCSF hoogleraren DeRisi, PhD, en Don Ganem, MD, ook heeft een diagnostische test voor het virus in verband met Proventricular dilatatie Disease, of PDD, waardoor de dierenartsen de hele wereld om de verspreiding van het virus. Results of the study will be published in Virology Journal and will appear online in August. Resultaten van het onderzoek zullen worden gepubliceerd in Journal Virologie en zal verschijnen online in augustus. The findings also will be presented in full at the August 11 annual meeting of the Association of Avian Veterinarians, in Savannah, GA. De resultaten ook zullen worden gepresenteerd in volle op 11 augustus de jaarlijkse bijeenkomst van de Association of Avian Veterinarians, in Savannah, GA. The new virus, which the team named Avian Bornavirus (ABV), is a member of the bornavirus family, whose other members cause encephalitis in horses and livestock. Het nieuwe virus, dat het team de naam Aviaire Bornavirus (vol), is lid van de bornavirus gezin, waarvan de andere leden veroorzaken encefalitis in paarden en vee. Working with veterinarians on two continents, the group isolated this virus in 71 percent of the samples from infected birds, but none of the healthy individuals. Werken met dierenartsen op twee continenten, de groep geďsoleerde dit virus in 71 procent van de monsters van geďnfecteerde vogels, maar geen van de gezonde individuen.
Posted by NatureRevMicrobiol to bornavirus birds on Sat Aug 02 2008 at 17:41 UTC | info | related Gepost door NatureRevMicrobiol te bornavirus vogels op za augustus 02 2008 bij 17:41 UTC | info | gerelateerd


johanblok
Website Member
Posts :1971

Website Member
2008-08-14 - 22:12:11 send message to johanblok

Het is erg mooi dat men het virus heeft kunnen identificeren. Alleen de weg naar een test, laat staan een behandeling is nog zeer lang.

Zoals de tekst ook zegt: men kan nu, na identificatie van het virus, pas beginnen met onderzoek naar het verband met de ziekteverschijnselen en epidemologie. Daarnaast is heeft men het aangetoffen in 71% van de gevallen en nooit in gezonde dieren. Dat wil zeggen dat men voor 29% van de vogels het geidentificeerde virus niet heeft kunnen vinden. Mogelijk heeft men nog niet helemaal gevonden wat men zocht, of is het virus lang niet in alle gevallen goed detecteerbaar. Vermoedelijk het laatste, wat aangeeft dat een zinvolle, d.w.z. betrouwbare, test zeker nog niet binnen bereik ligt.


medaar
Geroyeerd
Posts :1001

Geroyeerd
2008-08-15 - 21:55:30 send message to medaar

Ben niet mee. zo ver zoeken. Denkt dat je Student. bent.


wiechmann
Website Member
Posts :944

Website Member
2008-08-22 - 23:22:13 send message to wiechmann

als er mensen zijn die een vogel hebben met vermoeden van kds wil die dan met mij contact opnemen het is in het belang van het onderzoek hierboven.



Pagina : 1

Plaats een reactie



Er zijn in totaal 192 bezoekers op de site, waarvan 7 leden.

Aantal mensen in chat: 1
attie11,
Copyright 1998-2022,
Laatste update: 31 oktober 2022
e-mail: info@vogelarena.com
kinderopvang in Enschede